Regenerative endodontic therapy

Regenerative endodontic therapy – What is it?

Regenerative endodontic therapy technique for the revitalization of a necrotic immature tooth.

  • Tooth must be necrotic pulp with immature apex
  • Minimal to no dentinal manipulation
  • Place intracanal medicament (usually triple antibiotic) DAP better cause no stain of minocycline (metronidazole and ciprofloxacin) Sabrah 2013
  • mTAP (modified TAP) ciprofloxacin, metronidazole, cefaclor Thibodea 2007 Jan/Feb Ped Dent. Showed no stain but Akcay 2014 JOE said did.  Akcay said only DAP=no stain
  • Seal
Regenerative endodontic therapy

The color of teeth after 3 weeks according to the groups: (A) control group, (B) calcium hydroxide, (C) DAP, (D) TAP with minocycline, (E) with doxycycline, (F) with amoxicillin, and (G) with cefaclor.

Step by step for regenerative endodontic therapy with ADA dental codes

Step 1 Code 3351 Debride without dentinal wall manipulation and irrigate with 1.25%-3% NaOCl, place triple antibiotic, and seal.

Interim step if needed 3552 Repeat step 1

Step 2 3354 pulpal regeneration Remove medicine with 1.25%-3% NaOCL, EDTA (CA?), create blood clot, place PRF?, seal MTA and filling.  Do not use vasoconstrictor.

Ref 1

Regenerative endodontic therapy research

10% citric acid could give a better biological response than EDTA according to Ivica 2019 JOE.

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